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抑制剂 & 化合物

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重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T38160 STING Agonist 1a

STING agonist 1a is an agonist of stimulator of interferon genes (STING).1It induces expression of an IRF-inducible SEAP reporter gene in a cell-based assay (EC50= 16.77 μM). STING agonist 1a (12.5-100 μM) induces expression of IFN-β, IL-6, and chemokine (C-X-C motif) ligand 10 (CXCL10) in THP-1 cells, an effect that can be reversed by STING knockout or the STING inhibitor H-151 . 1.Hou, H., Yang, R., Liu, X., et al.Discovery of triazoloquinoxaline as novel STING agonists via structure-based vir...

化合物

STING Agonist 1a
Cat.No: T38160
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPJ-00018 CCL16 Protein, Human, Recombinant

NCC-4,Lymphocyte and Monocyte Chemoattractant,LMC,NCC4,HCC-4...

Human E. coli
CCL16 is a member of CC chemokine family. CCL16 cDNA encodes a 120 amino acid peptide along with a 23 amino acids signal peptide that is cleaved to generate 97 amino acid protein. CCL16 is distantly related to other CC chemokines, showing less than 30% sequence identity. CCL16 elicits its effects on cells by interacting with cell surface chemokine receptors such as CCR1, CCR2, CCR5 and CCR8. Recombinant CCL16 has been shown to chemoattract human monocytes and THP1 cells but not resting lymphocyt...
TMPY-01751 DR3/TNFRSF25 Protein, Human, Recombinant (hFc)

TRAMP,TR3,WSL-1,TNFRSF12,DR3,WSL-LR,tumor necrosis factor re...

Human HEK293 Cells
DR3/TNFRSF25 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.9 kDa and the accession number is Q93038-10.
TMPY-05760 DR3/TNFRSF25 Protein, Human, Recombinant (hFc), Biotinylated

TRAMP,tumor necrosis factor receptor superfamily, m...

Human HEK293 Cells
DR3/TNFRSF25 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.9 kDa and the accession number is Q93038-10.
TMPY-00961 ADAM15 Protein, Human, Recombinant (His)

MDC15,ADAM metallopeptidase domain 15

Human HEK293 Cells
ADAM15 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 54 kDa and the accession number is Q13444-10.
TMPY-02300 BIN1 Protein, Human, Recombinant (His)

AMPHL,bridging integrator 1,AMPH2,SH3P9

Human E. coli
Amphiphysin 2, also named bridging integrator-1 (BIN1) or SH3P9, Amphiphysin2/BIN1 is a crescent-shaped N-BAR protein playing a key role in forming deeply invaginated tubes in muscle T-tubules, has been recently implicated in rare and common diseases affecting different tissues and physiological functions. BIN1 downregulation is linked to cancer progression and also correlates with ventricular cardiomyopathy and arrhythmia preceding heart failure. Increased BIN1 expression is linked to increased...

重组蛋白

CCL16 Protein, Human, Recombinant
Cat.No: TMPJ-00018
Species: Human
Expression System: E. coli
DR3/TNFRSF25 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-01751
Species: Human
Expression System: HEK293 Cells
DR3/TNFRSF25 Protein, Human, Recombinant (hFc), Biotinylated
Cat.No: TMPY-05760
Species: Human
Expression System: HEK293 Cells
ADAM15 Protein, Human, Recombinant (His)
Cat.No: TMPY-00961
Species: Human
Expression System: HEK293 Cells
BIN1 Protein, Human, Recombinant (His)
Cat.No: TMPY-02300
Species: Human
Expression System: E. coli
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